Prevalence and Associated Factors of Impaired Renal Function in Chinese Children: The China Health and Nutrition Survey
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AIM: To assess the prevalence of impaired renal function and its associated factors in Chinese children.
METHODS: Children aged 7-18 years in China Health and Nutrition Survey (CHNS) 2009 were included as participants, and their anthropometric measurements, blood pressure (BP) and biochemical parameters were taken for analysis. The estimated glomerular filtration rate (eGFR) was calculated by using the Schwartz "original" formula.
RESULTS: The prevalence of estimated glomerular filtration rate (eGFR) < 90 ml/min/1.73 m2 and < 75 ml/min/1.73 m2 was 10.09% (95% CI: 8.03-12.11) and 1.01% (95% CI: 0.38-1.77) respectively. The prevalence of impaired renal function (eGFR < 60 ml/min/1.73 m2 ) was 0.25%. Age was detected as a negative associated factor whereas hyperuricemia and elevated total cholesterol (TC) were positively associated factors for subjects with eGFR < 90 ml/min/1.73 m2 . In the group of eGFR < 75 ml/min/1.73 m2 , only elevated TC was related to the increased odds of decreased eGFR.
CONCLUSIONS: Our findings underscore the need for large-scale programs to detect and treat the early-stage impaired renal function in the paediatric population in China.
JOUR
Song, Peige
Wang, Manli
Chang, Xinlei
Wang, Jiawen
Wei, Wei
An, Lin
2019
Nephrology
24
2
195-201
PMC5891388
2602