Sleep Duration and Abnormal Serum Lipids: The China Health and Nutrition Survey
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OBJECTIVE: To examine the associations between sleep duration and total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein B (ApoB), apolipoprotein A1 (ApoA1), and lipoprotein (a) [Lp(a)]. METHODS: The present study analyzed 8574 adults from the China Health and Nutrition Survey (2009). Sleep duration was classified into 6, 7, 8, 9, and 10h. Age, education, occupation, current smoking, current drinking, physical activity, body mass index, hypertension, and diabetes were adjusted as confounders in gender-stratified multiple logistic regression models. RESULTS: Compared with women reporting 8h sleep duration, the odds ratios (ORs) and 95% confidence intervals (CIs) of high TC for those with 6, 7, 9, and 10h were 1.65 (1.32-2.06), 1.19 (1.00-1.43), 1.11 (0.89-1.39), and 1.27 (1.02-1.60) after adjusting for confounders. Likewise, the ORs (95% CIs) of high LDL-C were 1.71 (1.28-2.29), 1.36 (1.05-1.76), 1.04 (0.74-1.46), and 1.09 (0.78-1.53), whereas those of high ApoB were 1.80 (1.34-2.42), 1.15 (0.88-1.52), 0.95 (0.66-1.35), and 1.00 (0.70-1.43) for women with 6, 7, 9, and 10h sleep duration, respectively. These associations were not statistically significant in men. CONCLUSIONS: Both shorter and longer sleep durations were associated with higher risks of abnormal serum lipid profiles in women but not in men.
JOUR
Zhan, Yiqiang
Chen, Ruoqing
Yu, Jinming
2014
Sleep Medicine
15
7
833-9
2155