Air Pollution and Pulmonary Tuberculosis: A Nested Case-Control Study among Members of a Northern California Health Plan

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Citation

Smith, Genee S.; Van Den Eeden, Stephen K.; Garcia, Cynthia A.; Shan, Jun; Baxter, Roger P.; Herring, Amy H.; Richardson, David B.; Van Rie, Annelies T.; Emch, Michael E.; & Gammon, Marilie D. (2016). Air Pollution and Pulmonary Tuberculosis: A Nested Case-Control Study among Members of a Northern California Health Plan. Environmental Health Perspectives, 124(6), 761-768. PMCID: PMC4892908

Abstract

BACKGROUND: Ecologic analyses, case-case comparisons, and animal experiments suggest positive associations between air pollution and tuberculosis.
OBJECTIVES: We evaluated this hypothesis in a large sample which yields results more applicable to the general population.
METHODS: We conducted a case-control study nested within a cohort of Kaiser Permanente of Northern California members. All active pulmonary tuberculosis (TB) cases newly diagnosed from 1996-2010 (n=2309) were matched to two controls (n=4604) by age, gender, and race/ethnicity on the index date corresponding with the case diagnosis date. Average individual-level concentrations of carbon monoxide (CO), nitrogen dioxide (NO

URL

http://dx.doi.org/10.1289/ehp.1408166

Reference Type

Journal Article

Year Published

2016

Journal Title

Environmental Health Perspectives

Author(s)

Smith, Genee S.
Van Den Eeden, Stephen K.
Garcia, Cynthia A.
Shan, Jun
Baxter, Roger P.
Herring, Amy H.
Richardson, David B.
Van Rie, Annelies T.
Emch, Michael E.
Gammon, Marilie D.

PMCID

PMC4892908

ORCiD

Emch - 0000-0003-2642-965X