Citation
Lim, Jacqueline K.; Kilgore, Paul E.; Aiello, Allison E.; Foxman, Betsy; Letson, G. William; Jang, Gi-Young; Chung, Eunhee; Song, Young-Hwan; & Kim, Yun-Kyung (2015). Impact of Time to Treatment of Oseltamivir on Influenza Hospitalization Costs among Korean Children. Pediatrics International, 57(3), 393-400.Abstract
BACKGROUND: While oseltamivir is a common influenza treatment, there is a lack of data about the economic benefits of timely oseltamivir treatment.METHODS: From February 2004 through June 2007, 116 hospitalized children =15 years-of-age with laboratory-confirmed influenza who received oseltamivir treatment were identified through a retrospective medical chart review. Demographic, clinical, and cost data were abstracted and multivariable linear regression was used to assess the association between oseltamivir time-to-treatment and treatment-related cost among hospitalized children with laboratory-confirmed influenza.
RESULTS: Overall, 28 per cent (n=33) of patients were treated with oseltamivir >/= day-3 following admission. Influenza rapid diagnostics were used in a significantly lower proportion of patients treated with oseltamivir >/= day-3 of admission compared to those whose oseltamivir therapy started earlier. Multivariable linear regression showed that children who received oseltamivir 3+ days after admission were associated with a 60.84% ([95% CI, 32.59 - 95.11]) increase in treatment-related hospital charges, compared to those treated with oseltamivir on admission.
CONCLUSION: Delayed onset of oseltamivir was found to be associated with increased treatment-related hospital charges among children hospitalized with laboratory-confirmed influenza.
URL
http://dx.doi.org/10.1111/ped.12526Reference Type
Journal ArticleYear Published
2015Journal Title
Pediatrics InternationalAuthor(s)
Lim, Jacqueline K.Kilgore, Paul E.
Aiello, Allison E.
Foxman, Betsy
Letson, G. William
Jang, Gi-Young
Chung, Eunhee
Song, Young-Hwan
Kim, Yun-Kyung