Citation
Solana, Rafael; Tarazona, Raquel; Aiello, Allison E.; Akbar, Arne N.; Appay, Victor; Beswick, Mark; Bosch, Jos A.; Campos, Carmen; Cantisan, Sara; & Cicin-Sain, Luka, et al. (2012). CMV and Immunosenescence: From Basics to Clinics. Immunity and Ageing, 9(1), 23. PMCID: PMC3585851Abstract
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates "immunosenescence". This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.URL
http://dx.doi.org/10.1186/1742-4933-9-23Reference Type
Journal ArticleYear Published
2012Journal Title
Immunity and AgeingAuthor(s)
Solana, RafaelTarazona, Raquel
Aiello, Allison E.
Akbar, Arne N.
Appay, Victor
Beswick, Mark
Bosch, Jos A.
Campos, Carmen
Cantisan, Sara
Cicin-Sain, Luka
Derhovanessian, Evelyna
Ferrando-Martinez, Sara
Frasca, Daniela
Fulop, Tamas
Govind, Sheila
Grubeck-Loebenstein, Beatrix
Hill, Ann
Hurme, Mikko A.
Kern, Florian
Larbi, Anis
Lopez-Botet, Miguel
Maier, Andrea B.
McElhaney, Janet E.
Moss, Paul
Naumova, Elissaveta
Nikolich-Zugich, Janko
Pera, Alejandra
Rector, Jerrald L.
Riddell, Natalie
Sanchez-Correa, Beatriz
Sansoni, Paolo
Sauce, Delphine
van Lier, Rene
Wang, George C.
Wills, Mark R.
Zielinski, Maciej
Pawelec, Graham