Citation
Reyburn, Rita; Kim, Deok Ryun; Emch, Michael E.; Khatib, Ahmed; von Seidlein, Lorenz; & Ali, Mohammad (2011). Climate Variability and the Outbreaks of Cholera in Zanzibar, East Africa: A Time Series Analysis. American Journal of Tropical Medicine and Hygiene, 84(6), 862-869. PMCID: PMC3110353Abstract
Global cholera incidence is increasing, particularly in sub-Saharan Africa. We examined the impact of climate and ocean environmental variability on cholera outbreaks, and developed a forecasting model for outbreaks in Zanzibar. Routine cholera surveillance reports between 1997 and 2006 were correlated with remotely and locally sensed environmental data. A seasonal autoregressive integrated moving average (SARIMA) model determined the impact of climate and environmental variability on cholera. The SARIMA model shows temporal clustering of cholera. A 1°C increase in temperature at 4 months lag resulted in a 2-fold increase of cholera cases, and an increase of 200 mm of rainfall at 2 months lag resulted in a 1.6-fold increase of cholera cases. Temperature and rainfall interaction yielded a significantly positive association (P < 0.04) with cholera at a 1-month lag. These results may be applied to forecast cholera outbreaks, and guide public health resources in controlling cholera in Zanzibar.URL
http://dx.doi.org/10.4269/ajtmh.2011.10-0277Reference Type
Journal ArticleYear Published
2011Journal Title
American Journal of Tropical Medicine and HygieneAuthor(s)
Reyburn, RitaKim, Deok Ryun
Emch, Michael E.
Khatib, Ahmed
von Seidlein, Lorenz
Ali, Mohammad