Citation
Malik, Vasanti S.; Popkin, Barry M.; Bray, George A.; Després, Jean-Pierre; Willett, Walter C.; & Hu, Frank B. (2010). Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes: A Meta-Analysis. Diabetes Care, 33(11), 2477-2483. PMCID: PMC2963518Abstract
Consumption of sugar-sweetened beverages (SSBs), which include soft drinks, fruit drinks, iced tea, energy and vitamin water drinks has risen across the globe. Regular consumption of SSBs has been associated with weight gain and risk of overweight and obesity but its role in the development of related chronic metabolic diseases, such as metabolic syndrome (MetSyn) and type 2 diabetes (T2DM), has not been quantitatively reviewed. Methods: We searched the MEDLINE database up to May 2010 for prospective cohort studies of SSB intake and risk of MetSyn, and T2DM. We identified 11 studies (3 for MetSyn; 8 for T2DM) for inclusion in a random effects meta-analysis comparing SSB intake in the highest to lowest quantiles in relation to risk of MetSyn and T2DM. Results: Based on data from these studies, including 310,819 participants and 15,043 cases of T2DM, individuals in the highest quantile of SSB intake (most often 1-2 servings/day) had a 26% greater risk of developing T2DM than those in the lowest quantile (none or < 1 serving/month) (RR:1.26 (95% CI: 1.12, 1.41)). Among studies evaluating MetSyn, including 19,431 participants and 5,803 cases, the pooled RR was 1.20 (95% CI: 1.02, 1.42). Conclusions: In addition to weight gain, higher consumption of SSBs is associated with development of MetSyn, and T2DM. These data provide empirical evidence that intake of SSBs should be limited to reduce obesity-related risk of chronic metabolic diseases.URL
http://dx.doi.org/10.2337/dc10-1079Reference Type
Journal ArticleYear Published
2010Journal Title
Diabetes CareAuthor(s)
Malik, Vasanti S.Popkin, Barry M.
Bray, George A.
Després, Jean-Pierre
Willett, Walter C.
Hu, Frank B.