Citation
Rahman, Amin ur; Rashid, Saqib; Noon, Rizwana; Samuel, Zeerak S.; Lu, Bing; Borgnakke, Wenche S.; & Williams, Ray C. (2005). Prospective Evaluation of the Systemic Inflammatory Marker C-Reactive Protein in Patients with End-Stage Periodontitis Getting Teeth Replaced with Dental Implants: A Pilot Investigation. Clinical Oral Implants Research, 16(1), 128-131.Abstract
Objectives: Serum C-reactive protein (CRP) has been shown to be a risk predictor for cardiovascular disease. Periodontal treatment reduces elevated CRP levels. The aim of this pilot investigation was to evaluate if dental implants placed after extractions in patients with end-stage periodontitis affect the serum CRP levels.Material and methods: Serum CRP levels in 10 subjects with end-stage periodontitis were measured prior to tooth extraction and placement of dental implants, and at 3-month intervals for a year post-operatively. Univariate repeated measures analysis of variance was used to estimate and test the changes in CRP levels over time.
Results: Mean CRP levels decreased significantly following tooth extraction and replacement with dental implants from 3.45 to 1.55 mg/dl after 12 months (P<0.01). Six-, 9-, and 12-month post-implant placement mean CRP values were statistically significantly different from the mean pre-operative CRP value (P<0.01).
Conclusions: The pilot data suggest that extraction of advanced periodontally involved teeth and their replacement with dental implants lead to a decrease in CRP levels, and dental implant placement does not change the lowered CRP levels over a 12-month period.
URL
http://dx.doi.org/10.1111/j.1600-0501.2004.01109.xReference Type
Journal ArticleYear Published
2005Journal Title
Clinical Oral Implants ResearchAuthor(s)
Rahman, Amin urRashid, Saqib
Noon, Rizwana
Samuel, Zeerak S.
Lu, Bing
Borgnakke, Wenche S.
Williams, Ray C.