Inhaled Nitric Oxide for Primary Pulmonary Hypertension in Pregnancy

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Citation

Lam, Garrett K.; Stafford, Renae E.; Thorp, John M., Jr.; Moise, Kenneth J., Jr.; & Cairns, Bruce A. (2001). Inhaled Nitric Oxide for Primary Pulmonary Hypertension in Pregnancy. Obstetrics & Gynecology, 98(5, Pt. 2), 895-898.

Abstract

Background: Primary pulmonary hypertension is a rare and dangerous entity in pregnancy. Previous studies have found a 35-50% maternal mortality rate in the peripartum period. To date, most reports have described treatment of these patients with diuretics, digoxin, and calcium-channel blockers.
Case: We describe the successful treatment of a primigravida with severe primary pulmonary hypertension. We used elective intubation before labor, inhaled nitric oxide therapy, and assisted vaginal delivery with epidural anesthesia that resulted in a viable infant and survival of the mother.
Conclusion: Nitric oxide can be used to successfully treat primary pulmonary hypertension in pregnancy.

URL

http://dx.doi.org/10.1016/s0029-7844(01)01549-6

Reference Type

Journal Article

Year Published

2001

Journal Title

Obstetrics & Gynecology

Author(s)

Lam, Garrett K.
Stafford, Renae E.
Thorp, John M., Jr.
Moise, Kenneth J., Jr.
Cairns, Bruce A.

ORCiD

Thorp - 0000-0002-9307-6690