Baseline Serum Biomarkers Predict Response to a Weight Loss Intervention in Older Adults with Obesity: A Pilot Study

Citation

Lynch, David H.; Rushing, Blake R.; Pathmasiri, Wimal; McRitchie, Susan; Batchek, Dakota J.; Petersen, Curtis L.; Gross, Danae C.; Sumner, Susan C. J.; & Batsis, John A. (2023). Baseline Serum Biomarkers Predict Response to a Weight Loss Intervention in Older Adults with Obesity: A Pilot Study. Metabolites, 13(7), 853. PMCID: PMC10385260

Abstract

Caloric restriction and aerobic and resistance exercise are safe and effective lifestyle interventions for achieving weight loss in the obese older population (>65 years) and may improve physical function and quality of life. However, individual responses are heterogeneous. Our goal was to explore the use of untargeted metabolomics to identify metabolic phenotypes associated with achieving weight loss after a multi-component weight loss intervention. Forty-two older adults with obesity (body mass index, BMI,

URL

http://dx.doi.org/10.3390/metabo13070853

Reference Type

Journal Article

Year Published

2023

Journal Title

Metabolites

Author(s)

Lynch, David H.
Rushing, Blake R.
Pathmasiri, Wimal
McRitchie, Susan
Batchek, Dakota J.
Petersen, Curtis L.
Gross, Danae C.
Sumner, Susan C. J.
Batsis, John A.

Article Type

Regular

PMCID

PMC10385260

Continent/Country

United States

State

Nonspecific

ORCiD

Batis - 0000-0002-2823-6651