Asian American/Pacific Islander and Hispanic Ethnic Enclaves, Neighborhood Socioeconomic Status, and Hepatocellular Carcinoma Incidence in California: An Update

Citation

Sangaramoorthy, Meera; Yang, Juan; Guan, Alice; DeRouen, Mindy C.; Tana, Michele M.; Somsouk, Ma; Thompson, Caroline A.; Gibbons, Joseph; Ho, Chanda; & Chu, Janet N., et al. (2022). Asian American/Pacific Islander and Hispanic Ethnic Enclaves, Neighborhood Socioeconomic Status, and Hepatocellular Carcinoma Incidence in California: An Update. Cancer Epidemiology, Biomarkers & Prevention, 31(2), 382-392. PMCID: PMC8825691

Abstract

BACKGROUND: Using more recent cancer registry data, we analyzed disparities in hepatocellular carcinoma (HCC) incidence by ethnic enclave and neighborhood socioeconomic status (nSES) among Asian American/Pacific Islander (AAPI) and Hispanic populations in California.
METHODS: Primary, invasive HCC cases were identified from the California Cancer Registry during 1988-1992, 1998-2002, and 2008-2012. Age-adjusted incidence rates (per 100,000 population), incidence rate ratios, and corresponding 95% confidence intervals were calculated for AAPI or Hispanic enclave, nSES, and the joint effects of ethnic enclave and nSES by time period (and the combination of the three periods), sex, and race/ethnicity.
RESULTS: In the combined time period, HCC risk increased 25% for highest versus lowest quintile of AAPI enclave among AAPI males. HCC risk increased 22% and 56% for lowest versus highest quintile of nSES among AAPI females and males, respectively. In joint analysis, AAPI males living in low nSES areas irrespective of enclave status were at 17% to 43% increased HCC risk compared with AAPI males living in areas of nonenclave/high nSES. HCC risk increased by 22% for Hispanic females living in areas of low nSES irrespective of enclave status and by 19% for Hispanic males living in areas of nonenclave/low nSES compared with their counterparts living in areas of nonenclave/high nSES.
CONCLUSIONS: We found significant variation in HCC incidence by ethnic enclave and nSES among AAPI and Hispanic populations in California by sex and time period.
IMPACT: Future studies should explore how specific attributes of enclaves and nSES impact HCC risk for AAPI and Hispanic populations.

URL

http://dx.doi.org/10.1158/1055-9965.EPI-21-1035

Reference Type

Journal Article

Year Published

2022

Journal Title

Cancer Epidemiology, Biomarkers & Prevention

Author(s)

Sangaramoorthy, Meera
Yang, Juan
Guan, Alice
DeRouen, Mindy C.
Tana, Michele M.
Somsouk, Ma
Thompson, Caroline A.
Gibbons, Joseph
Ho, Chanda
Chu, Janet N.
Cheng, Iona
Gomez, Scarlett L.
Shariff-Marco, Salma

Article Type

Regular

PMCID

PMC8825691

Data Set/Study

California Cancer Registry (CCR)

Continent/Country

United States

State

California

Race/Ethnicity

Asian American
Hispanic

ORCiD

Thompson, C. - 0000-0001-9990-9756