Citation
Pettaway, Curtis A.; Lamerato, Lois E.; Eaddy, Michael T.; Edwards, Jessie K.; Hogue, Susan L.; & Crane, Martin M. (2011). Benign Prostatic Hyperplasia: Racial Differences in Treatment Patterns and Prostate Cancer Prevalence. BJU International, 108(8), 1302-1308.Abstract
OBJECTIVE: To compare prostate cancer, prostate-related surgery and acute urinary retention rates, as well as associated healthcare resource use over 11 years in African American and Caucasian men with benign prostatic hyperplasia (BPH).PATIENTS AND METHODS: The BPH-related medical and surgical charges and events were determined for 398 African American men and 1656 Caucasian men followed for a mean of 10.2 years within a health maintenance organization. Racial differences in clinical outcomes were evaluated using time-to-event analysis, stratifying results by baseline prostate-specific antigen (PSA) values.
RESULTS: Risk of a prostate cancer diagnosis was 2.2 times greater in African American than Caucasian men (95% CI 1.48-3.35, P < 0.001) in analyses adjusting for serum PSA level. Although African Americans were more likely to receive medical therapy for symptoms of BPH than Caucasians (43.5% vs 37.2%, respectively; P= 0.029), there were no clinically meaningful differences with respect to subsequent acute urinary retention or BPH-related surgery between them, or BPH-related medical charges (US $407 vs US $405 per month).
CONCLUSION: As evidenced by this analysis of 'real-world' clinical practice, African Americans with BPH have a much greater risk of developing prostate cancer than similar Caucasian men highlighting the need for education and early detection in this population.
URL
http://dx.doi.org/10.1111/j.1464-410X.2010.09991.x.Reference Type
Journal ArticleYear Published
2011Journal Title
BJU InternationalAuthor(s)
Pettaway, Curtis A.Lamerato, Lois E.
Eaddy, Michael T.
Edwards, Jessie K.
Hogue, Susan L.
Crane, Martin M.
Article Type
RegularData Set/Study
Henry Ford Health System (HFHS) DatabaseContinent/Country
United StatesState
MichiganRace/Ethnicity
African-AmericanWhite