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Citation

Costantine, Maged M.; Rice, Madeline Murguia; Landon, Mark B.; Varner, Michael W.; Casey, Brian M.; Reddy, Uma M.; Wapner, Ronald J.; Rouse, Dwight J.; Tita, Alan T.N.; & Thorp, John M., Jr., et al. (2023). Oral Glucose Tolerance Test in Pregnancy and Subsequent Maternal Hypertension. American Journal of Perinatology, 40(16), 1803-1810. PMCID: PMC9108113

Abstract

OBJECTIVE: The aim of the study is to evaluate whether values and the shape of the glucose curve during the oral glucose tolerance test (OGTT) in pregnancy identify women at risk of developing hypertension (HTN) later in life.
METHODS: This category includes the secondary analysis of a follow-up from a mild gestational diabetes mellitus (GDM) study that included a treatment trial for mild GDM (nā€‰=ā€‰458) and an observational cohort of participants with abnormal 1-hour glucose loading test only (normal OGTT, nā€‰=ā€‰430). Participants were assessed at a median of 7 (IQR 6-8) years after their index pregnancy, and trained staff measured their blood pressure (systolic blood pressure [SBP]; diastolic blood pressure [DBP]). The association between values and the shape of the glucose curve during OGTT in the index pregnancy and the primary outcome defined as elevated BP (SBP

URL

http://dx.doi.org/10.1055/s-0041-1740007

Reference Type

Journal Article

Year Published

2023

Journal Title

American Journal of Perinatology

Author(s)

Costantine, Maged M.
Rice, Madeline Murguia
Landon, Mark B.
Varner, Michael W.
Casey, Brian M.
Reddy, Uma M.
Wapner, Ronald J.
Rouse, Dwight J.
Tita, Alan T.N.
Thorp, John M., Jr.
Chien, Edward K.
Peaceman, Alan M.
Blackwell, Sean C., for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network

Article Type

Regular

PMCID

PMC9108113

Continent/Country

United States of America

State

Nonspecific

ORCiD

Thorp - 0000-0002-9307-6690