Racial Disparities in Inpatient Clinical Presentation, Treatment, and Outcomes in Brain Metastasis

Download as .RIS

Citation

McCray, Edwin; Waguia, Romaric; de la Garza Ramos, Rafael; Price, Meghan J.; Williamson, Theresa; Dalton, Tara; Sciubba, Daniel M.; Yassari, Reza; Goodwin, Andrea; & Fecci, Peter, et al. (2022). Racial Disparities in Inpatient Clinical Presentation, Treatment, and Outcomes in Brain Metastasis. Neuro-Oncology Practice, 10(1), 62-70. PMCID: PMC9837769

Abstract

BACKGROUND: Few studies have assessed the impact of race on short-term patient outcomes in the brain metastasis population. The goal of this study is to evaluate the association of race with inpatient clinical presentation, treatment, in-hospital complications, and in-hospital mortality rates for patients with brain metastases (BM).
METHOD: Using data collected from the National Inpatient Sample between 2004 and 2014, we retrospectively identified adult patients with a primary diagnosis of BM. Outcomes included nonroutine discharge, prolonged length of stay (pLOS), in-hospital complications, and mortality.
RESULTS: Minority (Black, Hispanic/other) patients were less likely to receive surgical intervention compared to White patients (odds ratio [OR] 0.70; 95% confidence interval [CI] 0.66-0.74, p < 0.001; OR 0.88; 95% CI 0.84-0.93, p < 0.001). Black patients were more likely to develop an in-hospital complication than White patients (OR 1.35, 95% CI 1.28-1.41, p < 0.001). Additionally, minority patients were more likely to experience pLOS than White patients (OR 1.48; 95% CI 1.41-1.57, p < 0.001; OR 1.34; 95% CI 1.27-1.42, p < 0.001). Black patients were more likely to experience a nonroutine discharge (OR 1.25; 95% CI 1.19-1.31, p < 0.001) and higher in-hospital mortality than White (OR 1.13; 95% CI 1.03-1.23, p = 0.008).
CONCLUSION: Our analysis demonstrated that race is associated with disparate short-term outcomes in patients with BM. More efforts are needed to address these disparities, provide equitable care, and allow for similar outcomes regardless of care.

URL

http://dx.doi.org/10.1093/nop/npac061

Reference Type

Journal Article

Year Published

2022

Journal Title

Neuro-Oncology Practice

Author(s)

McCray, Edwin
Waguia, Romaric
de la Garza Ramos, Rafael
Price, Meghan J.
Williamson, Theresa
Dalton, Tara
Sciubba, Daniel M.
Yassari, Reza
Goodwin, Andrea
Fecci, Peter
Johnson, Margaret O.
Chaichana, Kaisorn
Goodwin, C. Rory

Article Type

Regular

PMCID

PMC9837769

Data Set/Study

U.S. National Inpatient Sample (NIS) Database

Continent/Country

United States of America

State

Nonspecific

Race/Ethnicity

White
Black
Hispanic

ORCiD

Goodwin - 0000-0002-5976-8167