Premature and Early Menopause among US Women with or at Risk for HIV

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Citation

Bullington, Brooke W.; Edmonds, Andrew; Ramirez, Catalina; Rahangdale, Lisa; Neal-Perry, Genevieve; Konkle-Parker, Deborah; Weiss, Deborah J.; Moran, Caitlin; Golub, Elizabeth T.; & Cejtin, Helen, et al. (2022). Premature and Early Menopause among US Women with or at Risk for HIV. Menopause, 29(6), 741-747. PMCID: PMC9177513

Abstract

OBJECTIVE: Little is known about the prevalence and treatment of premature and early menopause among people with HIV. We described premature and early menopause and subsequent hormonal treatment in a longitudinal cohort of women living with or at risk for HIV in the US.
METHODS: Data from the Women's Interagency HIV Study between 2008 and 2020 were analyzed to describe premature and early menopause among cohort participants under the age of 51.
RESULTS: Of 3,059 eligible women during the study period, 1% (n = 35) underwent premature menopause before age 41, 3% (n = 101) underwent menopause between ages 41 and 46, and 21% (n = 442) underwent menopause between ages 46 and 50, inclusive. Of participants who experienced menopause before age 41, between age 41 and 45, and between ages 46 and 50, 51%, 24%, and 7% (respectively) received either menopausal hormone therapy or hormonal contraception.
CONCLUSION: These findings suggest that disparities in receipt of recommended hormone therapy for premature and early menopause may contribute, in part, to evident health disparities, such as cardiovascular disease, osteoporosis, and overall mortality. They also suggest a substantial need for education among people experiencing early menopause and their providers, with the goal of improving access to hormone therapy based on guidelines to address health disparities and minimize future health consequences.

URL

http://dx.doi.org/10.1097/gme.0000000000001964

Reference Type

Journal Article

Year Published

2022

Journal Title

Menopause

Author(s)

Bullington, Brooke W.
Edmonds, Andrew
Ramirez, Catalina
Rahangdale, Lisa
Neal-Perry, Genevieve
Konkle-Parker, Deborah
Weiss, Deborah J.
Moran, Caitlin
Golub, Elizabeth T.
Cejtin, Helen
Seidman, Dominika
Kassaye, Seble
Wilson, Tracey E.
Sharma, Anjali
Adimora, Adaora A.
Knittel, Andrea K.

Article Type

Brief Report

PMCID

PMC9177513

Data Set/Study

Women's Interagency HIV Study

Continent/Country

United States of America

State

Nonspecific

Sex/Gender

Women

ORCiD

Bullington - 0000-0002-3341-087X