Citation
Lodge, Evans K.; Engel, Lawrence S.; Ferrando-MartÃnez, Sara; Wildman, Derek E.; Uddin, Monica; Galea, Sandro; & Aiello, Allison E. (2020). The Association between Residential Proximity to Brownfield Sites and High-Traffic Areas and Measures of Immunity. Journal of Exposure Science & Environmental Epidemiology, 30(5), 824-834. PMCID: PMC7483819Abstract
The mechanisms by which neighborhood environmental exposures influence health are poorly understood, although immune system dysregulation represents a potential biological pathway. While many neighborhood exposures have been investigated, there is little research on residential proximity to brownfield waste. Using biomarker data from 262 participants in the Detroit Neighborhood Health Study, we estimated the association between proximity to brownfields and heavy traffic and signal joint T-cell receptor excision circles (sjTRECs, a measure of naive T-cell production), C-reactive protein (CRP, a measure of systemic inflammation), and interleukin-6 (IL-6, a pro-inflammatory cytokine). We assessed residential proximityURL
http://dx.doi.org/10.1038/s41370-020-0226-2Reference Type
Journal ArticleYear Published
2020Journal Title
Journal of Exposure Science & Environmental EpidemiologyAuthor(s)
Lodge, Evans K.Engel, Lawrence S.
Ferrando-MartÃnez, Sara
Wildman, Derek E.
Uddin, Monica
Galea, Sandro
Aiello, Allison E.
Article Type
RegularPMCID
PMC7483819Data Set/Study
Detroit Neighborhood Health Study (DNHS)Continent/Country
United States of AmericaState
MichiganORCiD
Aiello - 0000-0001-7029-2537Lodge - 0000-0002-2222-5441