Citation
King, Elise R.; Garrett, Haley E.; Abernathy, Haley A.; Cassidy, Caitlin A.; Cabell, Cameron R.; Shook-Sa, Bonnie E.; Juliano, Jonathan J; Boyce, Ross M.; Aiello, Allison E.; & Ciccone, Emily J. (2023). Comparison of Capillary Blood Self-Collection Using the Tasso-SST Device with Venous Phlebotomy for Anti-SARS-COV-2 Antibody Measurement. Journal of Immunological Methods, 520, 113523. PMCID: PMC10528948Abstract
Measuring seroprevalence over time is a valuable epidemiological tool for improving our understanding of COVID-19 immunity. Due to the large number of collections required for population surveillance as well as concerns about potential infection risk to the collectors, self-collection approaches are being increasingly pursued. To advance this methodology, we collected paired venous and capillary blood samples by routine phlebotomy and Tasso-SST device respectively from 26 participants and measured total immunoglobulin (Ig) and IgG antibodies to the SARS-CoV-2 receptor binding domain (RBD) by enzyme-linked immunosorbent assay (ELISA) on both specimens. Qualitatively, no discrepancies were noted in binary results between Tasso and venipuncture-derived plasma. Furthermore, in vaccinated participants, correlation between Tasso and venous total Ig and IgG specific antibody quantitative levels was high (Total Ig:URL
http://dx.doi.org/10.1101/2023.03.13.23286935Reference Type
Journal ArticleYear Published
2023Journal Title
Journal of Immunological MethodsAuthor(s)
King, Elise R.Garrett, Haley E.
Abernathy, Haley A.
Cassidy, Caitlin A.
Cabell, Cameron R.
Shook-Sa, Bonnie E.
Juliano, Jonathan J
Boyce, Ross M.
Aiello, Allison E.
Ciccone, Emily J.