Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States

Citation

Robertson, McKaylee M.; Shamsunder, Meghana G.; Brazier, Ellen; Mantravadi, Mekhala; Zimba, Rebecca; Rane, Madhura S.; Westmoreland, Drew A.; Parcesepe, Angela M.; Maroko, Andrew R.; & Kulkarni, Sarah G., et al. (2022). Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States. Emerging Infectious Diseases, 28(11), 2171-2180. PMCID: PMC9622253

Abstract

We examined racial/ethnic disparities for COVID-19 seroconversion and hospitalization within a prospective cohort (n = 6,740) in the United States enrolled in March 2020 and followed-up through October 2021. Potential SARS-CoV-2 exposure, susceptibility to COVID-19 complications, and access to healthcare varied by race/ethnicity. Hispanic and Black non-Hispanic participants had more exposure risk and difficulty with healthcare access than white participants. Participants with more exposure had greater odds of seroconversion. Participants with more susceptibility and more barriers to healthcare had greater odds of hospitalization. Race/ethnicity positively modified the association between susceptibility and hospitalization. Findings might help to explain the disproportionate burden of SARS-CoV-2 infections and complications among Hispanic/Latino/a and Black non-Hispanic persons. Primary and secondary prevention efforts should address disparities in exposure, vaccination, and treatment for COVID-19.

URL

http://dx.doi.org/10.3201/eid2811.220072

Reference Type

Journal Article

Year Published

2022

Journal Title

Emerging Infectious Diseases

Author(s)

Robertson, McKaylee M.
Shamsunder, Meghana G.
Brazier, Ellen
Mantravadi, Mekhala
Zimba, Rebecca
Rane, Madhura S.
Westmoreland, Drew A.
Parcesepe, Angela M.
Maroko, Andrew R.
Kulkarni, Sarah G.
Grov, Christian
Nash, Denis

Article Type

Regular

PMCID

PMC9622253

Data Set/Study

Communities, Households and SARS/CoV-2 Epidemiology (CHASING) COVID Cohort Study

Continent/Country

United States of America

State

Nonspecific

Race/Ethnicity

Black
White
Asian
Hispanic

ORCiD

Parcesepe - 0000-0002-4321-125x