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Citation

Yang, Bingyi; Huang, Angkana T.; Garcia-Carreras, Bernardo; Hart, William E.; Staid, Andrea; Hitchings, Matt D. T.; Lee, Elizabeth C.; Howe, Chanelle J.; Grantz, Kyra H.; & Wesolowksi, Amy, et al. (2021). Effect of Specific Non-Pharmaceutical Intervention Policies on Sars-Cov-2 Transmission in the Counties of the United States. Nature Communications, 12(1), 3560. PMCID: PMC8195990

Abstract

Non-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (R(eff)) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median R(eff) below 1 when combined with either stay at home orders (median R(eff) 0.97, 95% confidence interval (CI) 0.58-1.39) or face masks (median R(eff) 0.97, 95% CI 0.58-1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.

URL

http://dx.doi.org/10.1038/s41467-021-23865-8

Reference Type

Journal Article

Year Published

2021

Journal Title

Nature Communications

Author(s)

Yang, Bingyi
Huang, Angkana T.
Garcia-Carreras, Bernardo
Hart, William E.
Staid, Andrea
Hitchings, Matt D. T.
Lee, Elizabeth C.
Howe, Chanelle J.
Grantz, Kyra H.
Wesolowksi, Amy
Lemaitre, Joseph C.
Rattigan, Susan M.
Moreno, Carlos A.
Borgert, Brooke A.
Dale, Celeste
Quigley, Nicole
Cummings, Andrew
McLorg, Alizée
LoMonaco, Kaelene
Schlossberg, Sarah
Barron-Kraus, Drew
Shrock, Harrison
Lessler, Justin
Laird, Carl D.
Cummings, Derek A. T.

Article Type

Regular

PMCID

PMC8195990

Continent/Country

United States of America

State

Nonspecific

ORCiD

Lessler - 0000-0002-9741-8109