Assessing the Global Threat from Zika Virus

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Citation

Lessler, Justin; Chaisson, Lelia H.; Kucirka, Lauren M.; Bi, Qifang; Grantz, Kyra H.; Salje, Henrik; Carcelen, Andrea C.; Ott, Cassandra T.; Sheffield, Jeanne S.; & Ferguson, Neil M., et al. (2016). Assessing the Global Threat from Zika Virus. Science, 353(6300), aaf8160. PMCID: PMC5467639

Abstract

First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.

URL

http://dx.doi.org/10.1126/science.aaf8160

Reference Type

Journal Article

Year Published

2016

Journal Title

Science

Author(s)

Lessler, Justin
Chaisson, Lelia H.
Kucirka, Lauren M.
Bi, Qifang
Grantz, Kyra H.
Salje, Henrik
Carcelen, Andrea C.
Ott, Cassandra T.
Sheffield, Jeanne S.
Ferguson, Neil M.
Cummings, Derek A. T.
Metcalf, C. Jessica E.
Rodriguez-Barraquer, Isabel

Article Type

Review

PMCID

PMC5467639

ORCiD

Lessler - 0000-0002-9741-8109