Citation
Jiang, Chao Qiang; Lessler, Justin; Kim, Lina; Kwok, Kin On; Read, Jonathan M.; Wang, Shuying; Tan, Lijiu; Hast, Marisa A.; Zhu, Huachen; & Guan, Yi, et al. (2017). Cohort Profile: A Study of Influenza Immunity in the Urban and Rural Guangzhou Region of China: The Fluscape Study. International Journal of Epidemiology, 46(2), e16. PMCID: PMC6251537Abstract
Southern China plays an important role in the evolution of influenza viruses because of the combination of a large population, year-round influenza virus circulation and strong global connectivity. Guangzhou is one of the largest cities in China, characterized by a rapidly decreasing population density gradient as one moves away from the city centre. Prompted by studies suggesting an important role for southern China in global influenza diversity and new methods for understanding influenza immunity, the Fluscape cohort was started in and around Guangzhou to explain temporal and spatial patterns of influenza incidence in urban and rural settings, using contact surveys and serology. The aims of the cohort study are: to measure patterns of immunity to previous influenza viruses, which should vary substantially at the household and village levels across this community; and to measure large-scale patterns of immunity to recent and historic strains in individuals over their lifetime.URL
http://dx.doi.org/10.1093/ije/dyv353Reference Type
Journal ArticleYear Published
2017Journal Title
International Journal of EpidemiologyAuthor(s)
Jiang, Chao QiangLessler, Justin
Kim, Lina
Kwok, Kin On
Read, Jonathan M.
Wang, Shuying
Tan, Lijiu
Hast, Marisa A.
Zhu, Huachen
Guan, Yi
Riley, Steven
Cummings, Derek A. T.