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Citation

Gorret, Abalinda M.; Muhindo, Rabbison; Baguma, Emma; Ntaro, Moses; Mulogo, Edgar M.; Deutsch-Feldman, Molly; Juliano, Jonathan J.; Nyehangane, Dan; & Boyce, Ross M. (2021). Comparison of Capillary versus Venous Blood for the Diagnosis of Plasmodium Falciparum Malaria Using Rapid Diagnostic Tests. Journal of Infectious Diseases, 224(1), 109-113. PMCID: PMC8491838

Abstract

We enrolled 250 febrile children in western Uganda to compare the results of malaria rapid diagnostic tests when using capillary versus venous blood. Participants were tested with four different RDT types. PCR testing was performed as the reference standard. Sensitivity and specificity were broadly similar across RDT types and sampling method. Agreement between sample type was high, ranging from 0.95 to 0.99. When following the manufacturer's recommended interpretation, only five tests would have resulted in a different clinical diagnosis. These results demonstrate that malaria RDTs perform similarly when using capillary or venous blood in febrile children with P. falciparum malaria.

URL

https://doi.org/10.1093/infdis/jiab032

Reference Type

Journal Article

Year Published

2021

Journal Title

Journal of Infectious Diseases

Author(s)

Gorret, Abalinda M.
Muhindo, Rabbison
Baguma, Emma
Ntaro, Moses
Mulogo, Edgar M.
Deutsch-Feldman, Molly
Juliano, Jonathan J.
Nyehangane, Dan
Boyce, Ross M.

Article Type

Brief Report

PMCID

PMC8491838

Continent/Country

Uganda

ORCiD

Boyce, R - 0000-0002-9489-6324