Citation
Batsis, John A.; Miranda, William R.; Prasad, Chaithra; Collazo-Clavell, Maria L.; Sarr, Michael G.; Somers, Virend K.; & Lopez-Jimenez, Francisco (2016). Effect of Bariatric Surgery on Cardiometabolic Risk in Elderly Patients: A Population-Based Study. Geriatrics & Gerontology International, 16(5), 618-624. PMCID: PMC4662917Abstract
AIM: Obesity is a major cardiovascular (CV) risk factor. Bariatric surgery (BSx) is an approved therapeutic alternative for class II-III obesity, but little evidence focuses on older adults. We assessed the effect of BSx on cardiometabolic variables and long-term CV risk in older adults.METHODS: We carried out a population-based, observational study from 1990-2009, of 40 consecutive elderly (age ≥60 years) residents of Olmsted County, MN, USA, with class II-III obesity treated with BSx at a University-based, academic health center. Data were obtained from the Rochester Epidemiology Project. Metabolic syndrome (MetS) was defined using American Heart Association/National Heart, Lung, Blood Institute (AHA/NHLBI) criteria (increased triglycerides, low high-density lipoprotein, increased blood pressure, increased glucose and body mass index as a modified measure of obesity instead of waist circumference). Change in CV risk factors, MetS prevalence, and impact on predicted CV risk using the Framingham risk score was ascertained at 1 year postoperatively and assessed statistically.
RESULTS: Mean age and body mass index were 64.4 ± 3.7 and 45.0 ± 6.3 kg/m(2) , respectively, and 28 out of 40 (70%) were women. One participant died during the 11-month study period after BSx from respiratory complications related to BSx, and one participant died at 2 years. Percentage of excess weight loss decreased by 57.5% at 1 year. Prevalence 1 year after BSx decreased for diabetes (57.5% to 22.5%; P < 0.03), hypertension 87.5% to 73.7% (P = 0.003), dyslipidemia (80% to 42.5%; P < 0.001) and sleep apnea (62.5% to 23.7%; P < 0.001).MetS prevalence decreased from 80% to 45% (P < 0.002). Baseline risk was 14.1%, which changed at follow up at 8.2%.
CONCLUSIONS: In older adults, BSx induces considerable weight loss, improves CV risk factors, decreases MetS prevalence and is an effective treatment in this population. Geriatr Gerontol Int 2016; 16: 618-624.
URL
https://doi.org/10.1111/ggi.12527Reference Type
Journal ArticleYear Published
2016Journal Title
Geriatrics & Gerontology InternationalAuthor(s)
Batsis, John A.Miranda, William R.
Prasad, Chaithra
Collazo-Clavell, Maria L.
Sarr, Michael G.
Somers, Virend K.
Lopez-Jimenez, Francisco