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Citation

Salje, Henrik; Tran Kiem, Cécile; Lefrancq, Noémie; Courtejoie, Noémie; Bosetti, Paolo; Paireau, Juliette; Andronico, Alessio; Hozé, Nathanaël; Richet, Jehanne; & Dubost, Claire-Lise, et al. (2020). Estimating the Burden of SARS-CoV-2 in France. Science, 369(6500), 208-211. PMCID: PMC7223792

Abstract

France has been heavily affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and went into lockdown on 17 March 2020. Using models applied to hospital and death data, we estimate the impact of the lockdown and current population immunity. We find that 2.9% of infected individuals are hospitalized and 0.5% of those infected die (95% credible interval: 0.3 to 0.9%), ranging from 0.001% in those under 20 years of age to 8.3% in those 80 years of age or older. Across all ages, men are more likely to be hospitalized, enter intensive care, and die than women. The lockdown reduced the reproductive number from 2.90 to 0.67 (77% reduction). By 11 May 2020, when interventions are scheduled to be eased, we project that 3.5 million people (range: 2.1 million to 6.0 million), or 5.3% of the population (range: 3.3 to 9.3%), will have been infected. Population immunity appears to be insufficient to avoid a second wave if all control measures are released at the end of the lockdown.

URL

http://dx.doi.org/10.1126/science.abc3517

Reference Type

Journal Article

Year Published

2020

Journal Title

Science

Series Title

Science. 2020 Jun 26;368(6498):eabd4246. doi: 10.1126/science.abd4246. PMID: 32586992

Author(s)

Salje, Henrik
Tran Kiem, Cécile
Lefrancq, Noémie
Courtejoie, Noémie
Bosetti, Paolo
Paireau, Juliette
Andronico, Alessio
Hozé, Nathanaël
Richet, Jehanne
Dubost, Claire-Lise
Le Strat, Yann
Lessler, Justin
Levy-Bruhl, Daniel
Fontanet, Arnaud
Opatowski, Lulla
Boelle, Pierre-Yves
Cauchemez, Simon

Article Type

Regular

PMCID

PMC7223792

Continent/Country

France

ORCiD

Lessler - 0000-0002-9741-8109