Skip to main content

Citation

Utazi, C. Edson; Thorley, Julia; Alegana, Victor A.; Ferrari, Matthew J.; Takahashi, Saki; Metcalf, C. Jessica E.; Lessler, Justin; Cutts, Felicity T.; & Tatem, Andrew J. (2019). Mapping Vaccination Coverage to Explore the Effects of Delivery Mechanisms and Inform Vaccination Strategies. Nature Communications, 10(1), 1633. PMCID: PMC6456602

Abstract

The success of vaccination programs depends largely on the mechanisms used in vaccine delivery. National immunization programs offer childhood vaccines through fixed and outreach services within the health system and often, additional supplementary immunization activities (SIAs) are undertaken to fill gaps and boost coverage. Here, we map predicted coverage at 1 × 1 km spatial resolution in five low- and middle-income countries to identify areas that are under-vaccinated via each delivery method using Demographic and Health Surveys data. We compare estimates of the coverage of the third dose of diphtheria-tetanus-pertussis-containing vaccine (DTP3), which is typically delivered through routine immunization (RI), with those of measles-containing vaccine (MCV) for which SIAs are also undertaken. We find that SIAs have boosted MCV coverage in some places, but not in others, particularly where RI had been deficient, as depicted by DTP coverage. The modelling approaches outlined here can help to guide geographical prioritization and strategy design.

URL

http://dx.doi.org/10.1038/s41467-019-09611-1

Reference Type

Journal Article

Year Published

2019

Journal Title

Nature Communications

Author(s)

Utazi, C. Edson
Thorley, Julia
Alegana, Victor A.
Ferrari, Matthew J.
Takahashi, Saki
Metcalf, C. Jessica E.
Lessler, Justin
Cutts, Felicity T.
Tatem, Andrew J.

Article Type

Regular

PMCID

PMC6456602

Continent/Country

LMICs
Nigeria
Ethiopia
Democratic Republic of Congo
Cambodia
Mozambique

ORCiD

Lessler - 0000-0002-9741-8109