Micro-Hotspots of Risk in Urban Cholera Epidemics

Citation

Azman, Andrew S.; Luquero, Francisco J.; Salje, Henrik; Mbaïbardoum, Nathan Naibei; Adalbert, Ngandwe; Ali, Mohammad; Bertuzzo, Enrico; Finger, Flavio; Toure, Brahima; & Massing, Louis Albert, et al. (2018). Micro-Hotspots of Risk in Urban Cholera Epidemics. Journal of Infectious Diseases, 218(7), 1164-1168. PMCID: PMC6107744

Abstract

Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimate the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200 meters during the 5 days immediately after case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions.

URL

http://dx.doi.org/10.1093/infdis/jiy283

Reference Type

Journal Article

Year Published

2018

Journal Title

Journal of Infectious Diseases

Author(s)

Azman, Andrew S.
Luquero, Francisco J.
Salje, Henrik
Mbaïbardoum, Nathan Naibei
Adalbert, Ngandwe
Ali, Mohammad
Bertuzzo, Enrico
Finger, Flavio
Toure, Brahima
Massing, Louis Albert
Ramazani, Romain
Saga, Bansaga
Allan, Maya
Olson, David
Leglise, Jerome
Porten, Klaudia
Lessler, Justin

Article Type

Regular

PMCID

PMC6107744

Continent/Country

Chad
Dominican Republic of the Congo

ORCiD

Lessler - 0000-0002-9741-8109