Leveraging multi-omics approaches to examine metabolic challenges of obesity in relation to cardiovascular diseases
Summary
There is limited understanding of the molecular mechanisms leading to cardiovascular disease (CVD), particularly in the context of obesity. Our studies aim to use genomics and metabolomics data to reveal mechanisms important in CVD, with strong potential for identifying biomarkers of CVD risk. Ultimately, this mechanistic framework will help identify novel therapeutic and nutritional targets to reduce the global burden of CVD.